CPS LIPIDICA CZECH VERSION CLINICAL PERFORMANCE STUDY LIPIDICA_01-2024 Pancreatic cancer is the 10th most common type of cancer. In 2022, more than 2,400 new cases were diagnosed in the Czech Republic. Approximately 2,100 patients will succumb to this disease, which is more than 87%. The main reason for the high percentage of deaths is the…
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CT INFURO CZECH VERSION CLINICAL TRIAL INFURO INFURO is designed as a monocentric, prospective, randomized, double-blind, cross-over Phase II clinical trial to test the safety and tolerability of furosemide inhalation in patients with dyspnea. Dyspnea is one of the most common symptoms in internal medicine. It has an adverse effect on patients' quality of life…
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CT M.A.R.S. CZECH VERSION CLINICAL TRIAL M.A.R.S. M.A.R.S. is a randomized, double-blind, placebo-controlled, multicenter study of the efficacy and safety of highly diluted atropine eye drops in slowing the progression of myopia in children,  a phase IIIb, three parallel-arm study designed to increase clinical knowledge of the effect of topical application of highly diluted atropine…
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CT MSC-EB CZECH VERSION CLINICAL TRIAL MSC-EB Safety and efficacy of allogenic adipose tissue-derived mesenchymal stromal cells in patients with epidermolysis bullosa: clinical trial phase I/II MSC-EB is a phase I/II clinical trial aiming to evaluate the safety and efficacy of the mesenchymal stromal cell-based medicinal product in patients with the rare congenital (genetic) disease…
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CT KDO_DC1311 CZECH VERSION CLINICAL TRIAL KDO_DC1311 Combined antitumor therapy with ex vivo manipulated dendritic cells producing interleukin-12 in children, adolescents and young adults with progressive, recurrent or primarily metastatic high-risk tumors KDO_DC1311 is a phase I/II clinical trial aiming to evaluate the safety and efficacy of the dendritic cell-based medicinal product in children, adolescent…
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CT CoVigi CZECH VERSION CLINICAL TRIAL CoVigi CoVigi is a multi-centre, phase IV post-marketing intervention trial that aims to monitor long-term safety and efficacy after vaccination against COVID-19. The trial was initiated by Masaryk University in cooperation with the University Hospital Brno and the Masaryk Memorial Cancer Institute. A total of 559 patients were enrolled…
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CT DisCoVeRy CZECH VERSION CLINICAL TRIALS DisCoVeRy A multicenter, adaptive, randomized study of safety and efficacy in hospitalized adult patients with COVID-19. The treatment of COVID-19 is still a major challenge for medical research, so new drugs are being explored or the use of existing drugs is being optimized. One of the new medicines is…
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CT HALF CZECH VERSION CLINICAL TRIAL HALF Prospective phase II clinical trial evaluating the efficacy and safety of tyrosine kinase inhibitor discontinuation after prior two-step dose reduction in patients with chronic myeloid leukemia in deep molecular remission The HALF clinical trial is designed as a prospective, multicentre, non-randomized, open-label phase II study to investigate the…
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CT REMED CZECH VERSION CLINICAL TRIAL REMED Effect of dexamethasone in patients with ARDS and COVID-19 – prospective, multi-centre, open-label, parallel-group, randomized controlled trial (REMED trial). COVID-19 is still a significant challenge for medical research, exploring new drugs or possible optimizing the use of existing drugs. One way to use an existing medicine is to…
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