CLINICAL TRIAL M.A.R.S.
M.A.R.S. is a randomised double-blind placebo-controlled multicentre study of the efficacy and safety of highly diluted atropine collyrium in retarding the development of myopia in children, a phase IIIb study with three parallel arms designed to increase clinical knowledge of the effect of topical application of highly diluted atropine on axial length growth in myopic eyes and to add to experimental knowledge of the efficacy and safety of this application.
The study was initiated by the University Hospital Brno in cooperation with Masaryk University. It is a paediatric clinical trial that will enrol a total of 288 patients in 5 centres in the Czech Republic.
OVERVIEW OF RECRUITMENT
Patient recruitment began on 29.6.2022 and will continue until 30.09.2024. As of 12.03.2024, 235 patients have been enrolled in the study.
Important links to the project
| Access to the REDCap database (for examiners) | Clinical Trials register – Search for 2020-002046-16 | Official project website |
| Publications |
Trial documents
Contact
Study sponsor:
FN Brno | prof. MUDr. Rudolf Autrata, CSc., MBA | autrata.rudolf@fnbrno.cz
Project manager:
Mgr. et Bc. Šárka Matyšková | matyskova@med.muni.cz