Project | Construction

CZECRIN_PharmTech

Modernization of technological units
CZECRIN for innovative clinical research.

Project information

Project name: CZECRIN_PHARMTECH

Reg. no: CZ.02.01.01/00/23_015/0008194

Programme: the Johannes Amos Comenius Operational Programme

Duration: 1. 1. 2024 – 31. 12. 2026

Annotation

The CZECRIN_PHARMTECH project is focused on the development and modernisation of the existing technological equipment of the Large Research Infrastructure CZECRIN.

The project activities will be aimed in particular at the acquisition of new and modernisation of the existing infrastructure facilities of the beneficiary and the partner so as to enable the development and improvement of the services provided to users of the infrastructure.

Research capacity for innovative clinical research and drug development through non-commercial clinical trials will be expanded.

News from the construction site

The equipment of individual technological units with instrumentation is being acquired. The acquired equipment is being put into operation and the services that will be offered to users in open access mode are being defined.

The submitted CZECRIN_PHARMTECH project is focused on the development and modernization of the TECHNOLOGY UNITS, specifically the modernization of the already existing GMP units that operate in the Good Manufacturing Practice (GMP) mode and the development of Pharmacology Units that will complement the portfolio of clinical research services offered in the open access mode to the research community.

Modernised GMP units

The implementation of the submitted project will modernize 2 GMP units.

GMP Unit

Centre for Cell and Tissue Engineering (CTEF cGMP)

The unit is located at the LRI CZECRIN partner in St. Anne’s University Hospital in Brno, FNUSA. It is focused on research, development and GMP production of somatic cell medicines, subsequently evaluated in clinical trials, especially within the CZECRIN|ONCO network.

GMP Unit

GMP MU unit

The unit is located within the Masaryk University (MU), Institute of Haematology and Blood Transfusion (IHT). This unit is part of the Institute of Pharmacology of the Masaryk University and is focused on research, development and GMP production of advanced therapeutics (ATMP).

Refined pharmacological units

The implementation of the project will also expand the services of the CZECRIN LRI within 2 Pharmacological Units:

Pharmacological units

Cellular unit

engaged in research in the fields of chemical and cellular pharmacology; the unit consists of the Bioanalytical Laboratory (Department of Pharmacology, Faculty of Medicine, MU), the Psychopharmacological Laboratory (a detached unit of the MU National Institute of Mental Health (NIMH) – this unit is part of the Institute of Pharmacology, Faculty of Medicine, MU) and the Molecular Pathophysiological Laboratory (Department of Pathophysiology, Faculty of Medicine, MU).

Pharmacological units

Protein unit

engaged in research of protein characteristics (Loschmidt Laboratory of Protein Engineering, Faculty of Science, MU).

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